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Methotrexate may cause serious skin reactions, including photosensitivity.

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there have been occasional reports of tetracyclines increasing the toxic effects of ergot alkaloids and methotrexate.
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your doctor may consider these medicines — such as azathioprine, cyclosporine, or methotrexate — if other treatments don t help.
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before using methotrexate tablets tell your doctor.

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